Journal Guide

JCI Insight is a peer-reviewed journal dedicated to biomedical research, ranging from preclinical to clinical studies.

JCI Insight publishes well-executed, high-quality, insightful research in all biomedical specialties, including Autoimmunity, Gastroenterology, Immunology, Metabolism, Nephrology, Neuroscience, Oncology, Pulmonology, Vascular Biology, and many others.

Papers submitted to JCI Insight should present a focused line of investigation that provides meaningful and impactful contributions to the understanding of the biology of disease or new therapeutic opportunities. JCI Insight articles may build on existing paradigms in the field or provide hypothesis-generating findings. Examples of studies suitable for JCI Insight include, but are not limited to, human genetics research, new mouse models of disease, in vivo studies of disease mechanisms, precision medicine, clinical and biomarker studies, and studies that provide new resources for the biomedical research community. Studies should include a relevant in vivo model system and/or a primary human cell or tissue model.

JCI Insight builds on the editorial leadership of the JCI, one of the oldest and most respected biomedical research journals, and is published by the American Society for Clinical Investigation (ASCI), a nonprofit honor organization of physician-scientists incorporated in 1908. JCI Insight serves to fulfill the ASCI’s objective to advance medical science through the publication of clinically relevant research reports. All articles published in JCI Insight are freely available online from the moment of publication.

The Journal of Clinical Investigation is a top-tier venue for critical advances in biomedical research. The JCI combines a 2009 Impact Factor of 15.387 with immediate free access to its articles to produce an ideal home for authors seeking the widest possible audience for their most important work. The journal is headed by Editor in Chief Dr. Laurence A. Turka (Harvard University, Beth Israel Deaconess Medical Center) and an Editorial Board of peer scientists at the University of Pennsylvania whose depth and experience ensures fair and competent peer review. Dr. Ushma Neill serves as the JCI's Executive Editor.In addition to the scholarly biomedical research articles that the JCI has always published, the journal accepts submissions in 2 other categories: Brief Reports and Technical Advances (see list). Brief Reports are discrete, highly significant findings reported in a shorter format. Technical Advances report new and important research tools and techniques with broad impact. These submissions should include application of the technique to a specific question relevant to understanding or treating a disease.The JCI participates in PubMed Central and deposits research articles upon publication of each issue, which satisfies the NIH Public Access Policy and other similar funding agency requirements.